Free open Job in North, South & Central America Fully Funded PhD Studentship in Malaria Co-infection Immunology at University of Utah
Stipend: University of Utah stipends are $28,500 per annum including health insurance and tuition as well as all research costs.
A PhD position has become available in the laboratory of Tracey Lamb at the University of Utah to determine the mechanisms by which EBV prevents the development of anti-malarial humoral immunity (journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1004858). Malaria is still a significant global problem killing around half a million annually, mostly children under the age of 5 years old. Our data suggests that acute EBV infection is a previously unidentified risk factor for the development of severe malaria in young children. Antibodies are a key mechanism of immune control of the Plasmodium parasites that cause malaria. Optimal T follicular helper cell responses are required to generate a robust and efficacious antibody response to control the parasitic infection. EBV suppresses T follicular helper cells that respond to Plasmodium infection during acute co-infection but the molecular mechanisms by which the happens are unknown. The project will make use of a mouse models of EBV/malaria co-infection along with analysis of human malaria samples from Cameroon to investigate the role of IL-10 in T follicular helper cell suppression. The successful applicant will become proficient in multiparameter flow cytometry, immunohistochemistry and cell culture, and will also have the opportunity to visit our field site in Yaounde, Cameroon in Central Africa.
This studentship will start in August 2019 and is based in the Department of Pathology in the Division of Microbiology and Immunology, a thriving and expanding department with a diverse expertise in infection immunology medicine.utah.edu/pathology/microbiology-immunology. Salt Lake City is a vibrant city that offers unrivaled access to the outdoors for hiking and skiing. The University of Utah is located within a 30 minute drive of 6 different ski resorts and is close to several of the National parks in Utah. The University of Utah offers free city travel on local buses and trains.
How to apply:
Please apply directly to the Principal Investigator, Tracey Lamb (firstname.lastname@example.org) including your CV and a letter of interest that outlines your research experience. Laboratory information can be found at www.bioscience.utah.edu/faculty/lamb
Candidate requirements: An upper second or 1st class honors degree with wet lab research experience. A masters degree is desirable, but not essential.
Funding: The position is NIH-funded. The successful candidate will receive the standard University of Utah stipend ($28,500 per annum) for 5 years. Research training costs are included, as are additional funds to support conference attendance.
Contacts: Dr. Tracey Lamb, Department of Pathology, University of Utah (email@example.com)