Job offer in london Research Associate in Molecular Biology of Microbial Cytochrome P450 Systems at University College London



This postdoctoral position is funded for up to 18 months in the first instance as part of a collaborative project on “PolyCYPs: optimising a preclinical platform tool to reduce pharmaceutical attrition rates” funded by the Innovate UK. The collaborative project is based in the laboratories of Prof. John Ward, Department of Biochemical Engineering, and is a collaboration with Hypha Discovery Ltd.

The post-holder in Biochemical Engineering will assist in the mutation and analysis of the target CYPs, and the manipulation of genes to enhance stability and expression in operons and in separate compatible plasmids. These will be cloned into robust expression host strains and systems developed for the broader use of these recombinant strains and cell-free enzyme extract products at laboratory and larger scales.

PhD in a relevant discipline (Biochemistry, Microbiology, Molecular Microbiology, Biological Chemistry, Biotechnology, etc).

Experience in one or more of the following areas: molecular biology techniques, enzyme cloning and expression, site directed mutagenesis, mutagenesis, microbiology, DNA transformation, electroporation or DNA transfer, enzyme screening, and assay development.

A job description and person specification can be accessed below.

UCL vacancy reference: 1643464

Applicants should apply online. To access further details about the position and how to apply please click on the ‘Apply’ button below.

If you have any queries regarding the application process, please contact Prof. John Ward (j.ward@ucl.ac.uk).

Closing Date: 21 May 2017.

Latest time for the submission of applications: 23:59.

Interview Date: TBC.

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