Job offer in england Research Associate (Lung Inflammation Biology) at The University of Manchester
The University of Manchester invites applications for the post of Research Associate. You will be based in the laboratory of Prof. Tracy Hussell and join the team as part of a new program of collaborative research with leading scientists at the pharmaceutical company GSK. The project is related to Chronic Obstructive Pulmonary Disease. Severe lung inflammation has consequences long after it has resolved, but the underlying mechanisms are unknown. Asthma, idiopathic pulmonary fibrosis, chronic obstructive pulmonary disease (COPD) and post-viral patients all experience recurrent infections that exacerbate the disease, and this accounts for the majority of hospitalisations and associated healthcare costs.
Airway macrophages play an important undisputed role in respiratory tract immunity, but their adaptation by the altered microenvironment in human lung disease is unexplored. We will define phenotypic, functional and transcriptomic boundaries between airway macrophages extracted from the healthy airspaces and their adaptation in the development of chronic lung disease. Our goal is to restore critical pathways that maintain immune health. We are looking for a Research Associate interested in developing the pathways that underpin pathogenic adaptation of airway macrophages in COPD. You will use lung tissue removed from patients undergoing cardiothoracic surgery and airway lavage samples from patients attending for routine bronchoscopy. The heterogeneity of cells present in these samples will be enumerated by CyTOF and/or flow cytometric analysis.
The School is strongly committed to promoting equality and diversity, including the Athena SWAN charter for gender equality in higher education. The School holds a Silver Award which recognises their good practice in relation to gender; including flexible working arrangements, family-friendly policies, and support to allow staff achieve a good work-life balance. We particularly welcome applications from women for this post. Appointment will always be made on merit. For further information, please visit:
Enquiries about the vacancy, shortlisting and interviews:
Name: Prof. Tracy Hussell.
Tel: 0161 275 4499
Tel: 01565 818 234
Date of external posting: 13 July 2017
This vacancy will close for applications at midnight on the closing date.
You may also be interested in the following vacancies:
BMH-10371 Research Associate (Imaging Immune Cell Biology)
BMH-10375 Research Associate (Dendritic Cells and Asthma)
BMH-10377 Research Associate (Immune Cell Communication
Further particulars including job description and person specification are available on the University of Manchester website – click on the ‘Apply’ button below to find out more.