Job offer in england ECMC Biomarker Validation Scientist at University of Birmingham



University of Birmingham – College of Medical and Dental Sciences

Institute of Cancer & Genomic Sciences

Full Time, fixed term for 4 years

The University of Birmingham has recently been successful in the renewal of the Cancer Research UK funded Experimental Cancer Medicine Centre (ECMC), the remit of which is to undertake translational and early-phase research in cancer. As part of this, an opportunity has arisen for a 4 year fully funded postdoctoral research position in the field of Biomarker development and validation, with a focus on genomic medicine assays.

The scientist will be responsible for developing and validating biomarker assays based on data from pre-clinical and translational studies carried out within the Birmingham ECMC. The assay platforms will be predominantly genomic, and as such the post will be placed with the College of Medical and Dental Sciences Genomic Medicine facility and Genomic Research laboratories (Group Leader: Dr Andrew Beggs). Oversight and strategic direction will be provided by the ECMC Management Board.

The genomic medicine facility has recently moved into state of the art facilities within the Institute of Biomedical Research complex. The core facility has access to 2x HiSeq 2500, 2xNextSeq 500, 3xMiSeq, a Fluidigm C1, Oxford Nanopore PromethIon and 10X Genomics Chromium instrumentation. Instruments are run on an “instrument access” model centrally with library preparation and sample preparation carried out within each core. We also have a Hamilton Robotics NGS Star liquid handling platform and Illumina NeoPrep for library preparation. We have access to a cloud based HPC facility on site (Bear CLOUD) as well as a dedicated research data network. We work together as part of NGS facilities across the University of Birmingham which also include MicrobesNG (Dr Nick Loman) and the Joint Centre for Environment Omics (Prof J Colbourne).

Research and development is an important part of this job and it is envisaged that this role will also allow an excellent candidate to develop their own research interests as well as significant opportunities for personal development.

The ideal candidate should hold first degree in area of specialism at a minimum of 2:1 and normally, a PhD in a relevant biological field (although equivalent experience will be considered). The candidate will be able to demonstrate experience in library preparation technologies for Illumina NGS instrumentation including troubleshooting, previous experience in a service based NGS environment and experience in liquid handling technologies/automated library preparation (ideally Hamilton Robotics based systems). Ideally, the candidate will also have eExperience in single cell library preparation techniques but training can be provided for this.

For informal inquiries: Dr Andrew Beggs (a.beggs@bham.ac.uk) 0121 414 7458

To download the details of this position and submit an electronic application online please click on the Apply Online button below, please quote the appropriate Job Ref in all enquiries, alternatively information can be obtained from http://www.birmingham.ac.uk/staff/jobs/index.aspx

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Location(s):

Midlands of England

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