Job offer in england Artificial Intelligence for Multi-Parametric Design of GPCR Ligands at University of Cambridge
Applications are invited for a 4-year BBSRC Industrial CASE studentship starting in October 2019 in the research group led by Dr Andreas Bender to work on a project which will aim to utilise, and develop further, recent developments in the Artificial Intelligence and data mining to develop computer algorithms for drug design. In particular, algorithms will be applied to and tested experimentally on a major protein target class of current drugs, namely G-Protein Coupled Receptors (GPCRs), a family of receptors linked to a wide range of human disease states, including Alzheimer’s disease and cancers.
The studentship is co-funded by Heptares Therapeutics (part of the Sosei Group); the project will include regular placements at the company’s research site, which will enable the student to learn directly from working in an industrial environment. Further information on the company is available at https://www.heptares.com.
Further information about Dr Bender’s research can be found at https://www.ch.cam.ac.uk/person/ab454.
Applicants should have (or expect to obtain) the equivalent of a UK first class or upper second-class honours degree (and preferably a Masters degree) in either a relevant natural science (e.g. chemistry, pharmacology, biochemistry, molecular biology) or computer science/related field (such as bioinformatics), with working knowledge of (or a strong interest in) the respective other field. Expertise in the areas of scientific programming (Python, C, Perl, or other languages), ligand- or structure-based drug design, and data mining packages (such as R, Scikit-learn, Matlab) would be very beneficial, as would be a general scientific understanding of chemical and biological information-gathering and an interest in drug discovery chemistry.
The studentship will provide a maintenance grant and tuition fees at the UK/EU rate, and is available to UK and EU students who meet the UK residency requirements of the Research Councils. Students from EU countries who do not meet the residency requirements may be eligible for a fees-only award. Owing to funding restrictions imposed by the sponsor, non-EU citizens cannot be considered.
Applications must be made online via the University Applicant Portal (see http://www.ch.cam.ac.uk/pgapp). Please note that there is an application fee. As part of your ‘Statement of Research Interest’ you must state that you are applying for the BBSRC studentship with Dr Bender. All applicants will also be considered for other studentships available in the Department of Chemistry.
Information about research in the Department of Chemistry is given at: http://www.ch.cam.ac.uk
Please quote reference MA16826 on your application and in any correspondence about this vacancy.